Nichelle is an American invention from the 1930s — a combination of Nicole (Greek Nikolaos, "victorious of the people") with the French -chelle (shell). Reprised Uhura across six Star Trek films (1979-1991). NAACP Image Awards Hall of Fame (2016).
Nichelle does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
In Pythagorean numerology the letters of Nichelle reduce to 5, The Seeker. This is a traditional interpretive system, not a factual claim about the name.