Alexis is from the Greek alexis — "defender, helper" — short form of Alexandros ("defender of men"). A top-25 US baby name from 1992 to 2007, peaking at #5 in 1995. Alexis Bledel (born 1981) — *American actress; played Rory Gilmore on The WB / CW's Gilmore Girls (2000-2007) for seven seasons; The Handmaid's Tale (Hulu 2017-2022) earned her the Primetime Emmy for Outstanding Guest Actress in a Drama Series (2017). Alexis Carrington Colby — Joan Collins's iconic character on ABC's Dynasty (1981-1989), one of the foundational television villains of 1980s prime-time soap; Golden Globe (1983). Alexis Rose — Annie Murphy's character on Schitt's Creek (CBC/Pop 2015-2020); Murphy won the Primetime Emmy for Outstanding Supporting Actress in a Comedy Series (2020), the year Schitt's Creek swept all major comedy categories. Alexis Smith (1921-1993) — Canadian American actress; Tony Award for Follies (1972). Alexis Sablone — American skateboarder and architect; one of the most-decorated street-skating women in X Games history. Alexis de Tocqueville is male (French historian, Democracy in America* 1835).
Featured throughout 1980s-2020s American television.
In Pythagorean numerology the letters of Alexis reduce to 7, The Seeker. This is a traditional interpretive system, not a factual claim about the name.