Ayo is from the Yoruba ayọ̀ — "joy, happiness." Ayo Edebiri (born 1995) — American actress and comedian of Nigerian-Barbadian heritage; plays Sydney Adamu on FX's The Bear (2022-present). Comedy Central staff writer (Pretty Smart, 2021). Time 100 Most Influential People (2024). Ayo Dosunmu is male (NBA player). Ayo & Teo — male sibling dance duo. Ayo Olatunji — Nigerian football executive.
Ayo does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
In Pythagorean numerology the letters of Ayo reduce to 5, The Seeker. This is a traditional interpretive system, not a factual claim about the name.