Lucille is the French feminine of Lucius — from the Latin lux (light). Lucille Ball (1911-1989) — *American actress whose I Love Lucy (1951-1957) was the most-watched US television show for four of its six seasons and remains among the most influential sitcoms in television history. Co-founded Desilu Productions with Desi Arnaz in 1950, becoming the first woman to head a major Hollywood production company (responsible for Star Trek, Mission: Impossible, The Untouchables*). The first female recipient of the International Radio and Television Society Gold Medal (1971). Presidential Medal of Freedom (1989). Honored on a US postage stamp.
Subject of Aaron Sorkin's Being the Ricardos (2021) starring Nicole Kidman.
In Pythagorean numerology the letters of Lucille reduce to 2, The Peacemaker. This is a traditional interpretive system, not a factual claim about the name.