Lupita is the Mexican-Spanish diminutive of Guadalupe — from the Arabic wadi al-lub ("wolf valley") via the Spanish shrine, and especially a name honoring Our Lady of Guadalupe, the apparition of the Virgin Mary to Saint Juan Diego on Tepeyac Hill outside Mexico City in 1531.
Lupita does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
In Pythagorean numerology the letters of Lupita reduce to 7, The Seeker. This is a traditional interpretive system, not a factual claim about the name.