Persis (Περσίς) is Greek for "Persian woman" — referring to someone from Persia. In Romans 16:12, Paul greets "the beloved Persis, who has worked hard in the Lord."
Persis was used in Puritan and Quaker families. Persis Khambatta (1948-1998) was the Indian actress in Star Trek: The Motion Picture.
Persis does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
In Pythagorean numerology the letters of Persis reduce to 5, The Seeker. This is a traditional interpretive system, not a factual claim about the name.