Priscilla comes from the Latin priscus, meaning "ancient" or "venerable." In the New Testament, Priscilla (often called Prisca) was a tentmaker and missionary who, with her husband Aquila, hosted Saint Paul.
Priscilla peaked at #127 in the U.S. in 1940. Priscilla Presley (born 1945), wife of Elvis, is the most famous 20th-century bearer. Today Priscilla is returning slowly — currently in the U.S. top 500.
Priscilla does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
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In Pythagorean numerology the letters of Priscilla reduce to 9, The Giver. This is a traditional interpretive system, not a factual claim about the name.