Roxana comes from the Old Persian Raoxshna, meaning "luminous" or "shining one" — from the same Indo-European root that gives English the word "radiance." The name was made famous by Roxana of Bactria (4th century BCE), the wife of Alexander the Great.
Roxana has been continuously used in Persian-speaking countries for two and a half millennia. In the West, Daniel Defoe's 1724 novel Roxana brought it briefly into English usage. Today the name sits in the U.S. top 800 and is rising — particularly in the Iranian diaspora.
Roxana reduces to six — the number of warmth and quiet beauty.